Glutathione (pronounced
'gloota-thigh-own') is the body's essential health ABC's - Antioxidant,
Blood Booster and Cell Detoxifer.
It is a tripeptide composed of
glutamic, cysteine and glycine. Glutathione is found in all cells in the
body, including the bile, the epithelial lining fluid of the lungs, and
- at much smaller concentrations - in the blood.
Glutathione is the smallest intracellular
non-protein thiol (molecule containing an S_H or sulfhydryl group)
molecule in the cells. This characteristic emphasizes its potent
antioxidant action and supports a multifaceted thiol exchange system,
which regulates cell activity.
This
small protein, produced naturally in the body, maintains these three
crucial protective functions. In fact, your life depends on glutathione.
Without it, your cells would disintegrate from unrestrained oxidation,
your body would have little resistance to metabolic acids, and your
liver would shrivel up from the eventual accumulation of acidic toxins.
Glutathione is not yet a household word. Even some
medical and holistic doctors who have heard the term may still have only
a vague idea of what it is. However, everyone will soon be talking
about this critical non-nutritive substance.
There was a
time when only scientists had heard of cholesterol and vitamins, but
today, everyone knows about them. Now the magnificence of glutathione is
becoming known.
In the last five years, over 25,000 medical
articles about this substance have been published, and the scientific
understanding of glutathione is gradually becoming common knowledge.
Each and every cell in the body is responsible for its own
supply of glutathione and must have the necessary raw materials in order
to produce it. Glutathione is always in great demand and is rapidly
consumed when we experience any sort of emotional or physical stress,
fatigue and even moderate exercise.
Some well-known causes of
glutathione depletion are as follows:
1) Acidic lifestyle
and diet
2) Air and Water pollution
3) Prescription and
recreational drugs
4) Ultraviolet and Radiation from cells phones,
computers, electrical cars, power lines, hair dryers, etc.
5)
Emotional and physical stress
6) Injury, trauma or burns
7)
Heavy metals
8) Cigarette smoke
9) Household chemicals
10)
Acetaminophen poisoning
11) Exhaust from motor vehicles
12)
Septic shock
All of these above factors lead to a build up of
acidic toxins that cause the loss of glutathione as a non-nutritive
buffer leading to cellular aging, dis-ease and finally death.
Why is Glutathione Essential to Health?
Glutathione's three major roles in the body are summarized by
the letters A-B-C.
- Anti-oxidant
- Blood Booster
- Cell Detoxifier
These are
the three critical processes driven by glutathione.
The Master Antioxidant
available at HealthPlusWealth.com
Over the past thirty years, researchers have explored
the role of antioxidants in good health as well as the treatment and
prevention of diseases involving oxidation or fermentation by metabolic
acids.
Well known and widely used antioxidants such as vitamin
A, vitamin E and selenium neutralize acid. They occur naturally in
nature, but not in the body. They must be introduced as part of a
balanced diet.
Given the critical role of antioxidants in good
health, it is not surprising that the body itself manufactures its own
natural antioxidants. The most important of these is glutathione.
Because all other antioxidants depend upon the presence of glutathione
to function properly, scientists call it 'the master antioxidant.'
Glutathione binds to toxins, forming a water-soluble complex -
which is ultimately excreted in the urine or bile as waste.
Food for the Blood
Elevated glutathione levels
enable the body to produce more white blood cells. White blood cells are
the body's garbage collectors and are the most important cells for
maintaining sterility of the body fluids.
Glutathione plays a
central role in the proper function of the white blood cells. Dr.
Bustavo Bounous, a leading glutathione expert, says, 'The limiting
factor in the proper activity of our lymphocytes (the white blood cells)
is the availability of glutathione.' In other words, healthy growth and
activity of the white blood cells depends upon glutathione's
availability. Put simply, glutathione is 'food' for the white blood
cells.
Cellular Detoxifier
Whether we know it or
not, we are continually inhaling and ingesting natural and synthetic
acidic toxins. They are unavoidable in these modern times both in our
polluted cities and our poorly engineered food supplies. When the body
has the health and the nourishment it needs, it works tirelessly to
eliminate acidic toxins and to protect itself.
But, increasing
levels of environmental pollution are depleting the body's store of
glutathione more and more rapidly.
Our main organ of
detoxification of acidic waste products is the lymphatic system and the
liver. This is the body's most concentrated source of glutathione.
Studies show that low glutathione levels lead to poor lymphatic
and liver function, causing more and more acidic toxins to circulate
through the body and resulting in damage to individual cells and organs.
Medical doctors today routinely use glutathione- promoting drugs
to detoxify victims of certain types of drug overdose.
Glutathione in Natural Medicine
Practitioners of
complementary and alternative medicine (CAM) have long advocated the use
of milk thistle for liver problems. It turns out that this herb works by
modestly elevating glutathione levels. The mineral selenium also
produces subtle elevations in glutathione by becoming integrated into
the glutathione peroxidase.
Glutathione in Traditional
Medicine
Emergency medical doctors, toxicologists and lung
and liver specialists are well acquainted with glutathione's therapeutic
uses. American physicians seeking ways to raise a patient's glutathione
levels can open the standard Physician's Desk Reference (PDR) and find
two options - the pharmaceutical drugs sold under the names Parlodex and
Mucomyst, and the natural dietary supplement found in natural foods
stores derived from whey protein isolate.
Drugs That Raise
Glutathione Levels
Pharmaceutical drugs like Procysteine,
OTC, OTX, Glutathione monoesters and Glutathione diesters have been used
to raise glutathione levels. However, they all produce side effects and
are unsuitable for long term use.
This pharmaceutical
non-nutritive chemical is used to break up mucus in lung dis-eases such
as cystic fibrosis, chronic bronchitis and asthma. It remains the
standard treatment for acetaminophen overdose.
Glutathione in
Health and Dis-Ease
It is believed that glutathione has
an important role to play in the prevention and treatment of
dis-ease. It may in the future be considered as important to health
as an alkaline diet, exercise and alkaline lifestyle.
Clinical tests show that raised glutathione
levels may address some of the eight major health issues of our time:
1) Cardiovascular
- Prevents
heart dis-ease - Shimizu H, Kiyohara Y, Kitazono T, Kubo M,
Ibayashi S, Fufishima M, Lida M. Relationship Between Plasma Glutathione
Levels and Cardiovascular Disease in a Defined Population: The Hisyama
Study. Stroke. 2004 Sep; 35(9):2072-7.
- Prevents stroke
- Paterson PG, Juurlink BH. Nutritional Regulation of
Glutathione in Stroke. Neurtox Res. 1999 Dec; 1(2): 99-112.
-
Prevents atherosclerosis - Coppola L, Grassia A, Giunta
R. Glutathione Improves Hemostatic and Hemorrheological Parameters in
Atherosclerotic Subject. Drugs Exp. Clin Res 1992 18:493-98
- Reverses artherosclerosis
-
Prevents reperfusion injury
2) Cancer
Cancer causing polychlorinated biphenyls (PCBs) have been
found to alter levels of glutathione compounds in experiments, which may
alter the body's resistance to certain types of cancer.
Glutathione deficiencies have been
linked to many forms of cancer.
- Prevents cancerous tissue
- Suppresses tumor growth
- Eliminates carcinogen - acids
-
Retards oxidative stress
- Prevents wasting dis-ease
- Eases
side effects of chemotherapy and radiotherapy
3) Pulmonary
Glutathione is the most efficient free radical
(acid) scavenger in the airways, and dozens of studies have confirmed
that free radical (acid) damage is a primary player in Chronic
Obstructive Pulmonary Disease. Rahman I, MacNee W. Oxidative Stress
and Regulation of Glutathione in Lung Inflammation. Eur Respir J. 2000
Sep; 16(3):534-54.
- Breaks up mucus - Rahman
I, MacNee W. Oxidative Stress and Regulation of Glutathione in Lung
Inflammation. Eur Respir J. 2000 Sep; 16(3):534-54
-
Cystic fibrosis - Glutathione neutralized harmful
oxidants introduced into the lungs or those released by cells. Exotoxins
from bacteria can overload the endobronchial terrain and feed the fires
of acidic inflammation. This staggering burden increases the oxidative
sensitivity of the CF lung, resulting in further injury of lung
parenchyma. Data supports evidence of a decrease in the antioxidant
tri-peptide glutathione (Roum JH, Buhl R, McElvaney NG, et al.
Systemic Deficiency of Glutathione in Systic Fibrosis. J Appl
Physiol 1993; 75:19-24).
- Asthma
- Chronic bronchitis
- Emphysema -
Lamson, David, MD, Grignall, Matthew, ND. The use of Nebulized
Glutathione in the Treatment of Emphysema: A Case Report. Altern Med
Review. 5(5);429-431, 2000 Oct.
- Pulmonary fibrosis
- Ishii T, Fujishiro M, Nakajima J, Teramoto S, Ouchi Y,
Matsuse T. Depletion of Glutathione S-Transferase P1 Induces Apoptosis
in Huamn Lung Fibroblasts. Exp Lung Res. 29(7);523-36, 2003 Oct-Nov.
4) Aging
Glutathione is
critically important to our brain as it is one of the most important
brain antioxidants. Glutathione helps preserve brain tissue by
preventing damage from free radicals (acids).
In addition to
quenching dangerous acids, glutathione also acts to recycle vitamin E
which also has the ability to reduce acidity in the brain. (Perlmutter
D., BrainRecovery.com July 2004, 5th ed:13)
-
Autism - Medical literature documents that an
out-fection can lead to a lowering of glutathione which participates in
detoxification, interacts with metallothioneins, and supports many
crucial aspects of immunity. A link between glutathione and autism
regression may derive from the fact that transient or chronic intestinal
problems can impair an infant's or toddler's nutritional status, thereby
minimizing the levels of amino-acids required for the production of
glutathione (McCandless, J. Children With Starving Brains. 2003, 2nd
ed; 252)
- Parkinson's Disease - Glutathione
helps to preserve brain tissue by preventing damage from free
radicals (acids) and destructive chemicals formed by the normal
processes of metabolism, toxic elements in the environment, and as a
normal response of the body to challenges by acidic agents or other
stresses. With the understanding that glutathione is important for
brain protection and that this protection many be lacking in the brains
of Parkinson's clients due to glutathione deficiency, it can be seen as
very beneficial. (Di Monte DA, Cahn P, Sandy MS. Glutathione in
Parkinson's Disease: A Link Between Oxidative Stress and Mitochondrial
Damage? An Neurol. 32 Suppl; S111-115, 1992.)
-
Alzheimer's Dis-ease - Woltjer, R.L., Hgheim W.,
Maezawa I., Vaisar T, Montine K.S., Montine T.J., Role of Glutathione in
Intracellular Amyloid-Alpha Recursor Protein/Carboxy- Terminal Fragment
Aggregation and Associated Cytotoxicity. J Neurochem. 2005 May; 93 (4):
1047-56.
- Huntington's Dis-Ease - Choo Y.S.,
Mao Z, Johnson GV, Lesort M. Increased Glutathione Levels In Cortical
Striatal Mitochondria of the R6/2 Huntington's Disease Mouse Model.
Neuroscience Letter. 2005 Sep 23; 386(1): 63-8.
-
Multiple Sclerosis - Calabrese V, Scapaginini G,
Ravagna A, Bella R, Butterfield DA, Calvani M, Pennisi G, Giuffrida
Stella AM. Disruption of Thiol Homeostasis and Nitrostative Stress in
the Cerebrospinal Fluid of Patients with Active Multiple Sclerosis:
Evidence for a Protective Role of Acetylcarnitine. 2003 Sep; 28(9):
1321-8. Mann CL, Davies MB, Aldersea J, Fryer AA, Jones PK, Ko Ko C,
Young C, Strange RC, Hawkins CP. Glutathione S-Transferase Polymorphisms
in MS: Their Relationship to Disability. Neurology. 2000 Feb
8;54(3):542-7.
- ALS - Tohgi H, Abe T, Yamazaki
K, Murata T, Ishizake E, Isobe C. Increase in Oxidized Products and
Reduction in Oxidized Glutathione in Cerborospinal Fluid From Patients
with Sporadic Form of Amyotrophic Lateral Sclerosis. Neurosci Lett. 1999
Feb 5; 260(3):204-6.
- Cataract
formation
- Macular degeneration
- Cancers of aging
-
Prostate problems
- Osteoarthritis -
Hammarqvist F, Luo JL, cotgreave IA, Andersson K, Wernerman J.
Skeletal Muscle Glutathione is Depleted In Critically Ill
Patients. Crit Care Med. 25(1):78-84 1997 Jan.
5)
Digestive
- Inflammatory bowel
dis-ease
- Hepatitis
- Malnutrition
- Pancreatitis
-
Peptic ulcer
6) Toxicology
-
Detoxifies certain drug overdoses - Acetaminophen has been
shown to reduce glutathione production, thus paving the way for
enhanced brain destruction by metabolic acids. (Perlmutter D. July 2004,
5th ed:108)
- Detoxifies substances in cigarette smoke and
auto exhaust - Rahman I, MacNee W. Lung Glutathione and Oxidative
Stress: Implications In Cigarette Smoke-Induced Airway Disease. Am J
Physiol. 277(6 Pt 1);1067-88, 1999 Dec.
- Detoxifies
pollutants including heavy metals and pesticides - Elevated
glutathione levels have been shown to protect tissue form lipid
peroxidation created by exposure to certain metals. Consider
infusions of glutathione to relieve the body burden of both neurotoxins
and metal toxicity, including mercury. (Foster, JS. Kane PC, Speight N.
The Detoxx Book. 2002;90)
- Prevents hearing loss from noise
pollution
- Detoxifies many well-known carcinogens
7)
Immunology
- Anti-viral for AIDS, hepatitis,
herpes, etc. - Low glutathione levels
in HIV clients may contribute to their immune deficiency since
glutathione plays an important role in the function of lymphocytes.
Some lymphocytes require adequate levels of glutathione in order to
function normally, and HIV induces oxidative stress that depletes the
cells of glutathione. Townsend DM, Tew KD, Tapero H. The Importance of
Glutathione in Human Disease. Biomed Pharmacother. 2003
May-June;57(3-4):145-55. Droge W, Holm E. Role of Cysteine and
Glutathione in HIV Infection and other Diseases Associated with Muscle
Wasting and Immunological Dysfunction. FASEB J, 11(13):1077-89 1997 Nov.
- Lyme Dis-Ease - Lyme dis-ease is a seriously
complex multi-system acidic inflammatory condition that is triggered
by bacterial exotoxins. Glutathione helps to remove exotoxic
and/or mycotoxic acids by forming a soluble compound with them,
which can then be excreted through the urine or gut. (Can
Glutathione Help Lyme Disease Sufferers? Excerpt from: The Glutathione
Report: Optimal Health with the Master Antioxidant, Issue 4, Volume 1,
May 2004).
- Natural antibiotic
- Chronic
fatigue syndrome - An article in the journal of Medical
Hypothesis proposed that glutathione, an antioxidant essential
for lymphocyte function, may be depleted in Chronic Fatigue
Syndrome patients. Glutathione is needed for both the immune
system and for aerobic muscular contraction. The authors proposed
that glutathione depletion by an activated immune system also causes the
muscular fatigue and myalgia associated with Chronic Fatigue Syndrome
(Bounous et al. 1999).
8) Metabolic
- Athletic
enhancement
- Decreases recovery time from physical stress
-
Supports hemoglobin in kidney failure -
Diabetes
- The blood and tissues of diabetics are marked by critically low
glutathione levels. Glutathione depletion may have adverse consequences
in diabetic clients independent of glycemic control, and it may weaken
the defense against oxidative stress. De Mattia G, Bravi MC,
Laurenti O, Cassone-Faldetta M, Armiento A, Ferri C, Falsano F.
Influence of Reduced Glutathione Infusion on Glucose Metabolism in
Patients with Non-insulin Dependent Diabetes Mellitus. Metabolism. 1998
Aug;47(8):433-8.
Glutathione provides the body with tools to
fight off these threats naturally. Healthy people also benefit from
elevated glutathione levels through an enhanced ability to fight off
acidic toxins, dis-ease, pre-cancerous cells and
the aging process itself. Diminished glutathione
levels are a symptom of aging and are particularly evident in such
aliments as Parkinson's dis-ease and Alzheimer's dis-ease.
Glutathione is also important to physically active
people. Many world-class athletes are discovering that
well-maintained glutathione levels gives them the edge over their
competitors, bringing greater strength and endurance, decreased recovery
time from injury, less muscle pain and fatigue, and muscle-promoting
activity.
Putting It All Together
1) Medical
science is still ascertaining all the critical roles played by
glutathione in dis-ease resistance and general good health. Clinical
evidence links low glutathione levels to the most common illnesses of
our time as well as newly emerging dis-eases.
2) As an essential
aid to health, glutathione works as the master
antioxidant in our body, optimizes the white blood cells
and detoxifies a long list of pollutants and carcinogens or acids.
The best way to raise glutathione levels is by eating foods that are
high in glutathione or concentrate precursor.
--------------------------------------------------
The
Real Glutathione Story ... "live is
Key!"
levels may address some of the eight major health issues of our time:
1) Cardiovascular
- Prevents
heart dis-ease - Shimizu H, Kiyohara Y, Kitazono T, Kubo M,
Ibayashi S, Fufishima M, Lida M. Relationship Between Plasma Glutathione
Levels and Cardiovascular Disease in a Defined Population: The Hisyama
Study. Stroke. 2004 Sep; 35(9):2072-7.
- Prevents stroke
- Paterson PG, Juurlink BH. Nutritional Regulation of
Glutathione in Stroke. Neurtox Res. 1999 Dec; 1(2): 99-112.
-
Prevents atherosclerosis - Coppola L, Grassia A, Giunta
R. Glutathione Improves Hemostatic and Hemorrheological Parameters in
Atherosclerotic Subject. Drugs Exp. Clin Res 1992 18:493-98
- Reverses artherosclerosis
-
Prevents reperfusion injury
2) Cancer
Cancer causing polychlorinated biphenyls (PCBs) have been
found to alter levels of glutathione compounds in experiments, which may
alter the body's resistance to certain types of cancer.
Glutathione deficiencies have been
linked to many forms of cancer.
- Prevents cancerous tissue
- Suppresses tumor growth
- Eliminates carcinogen - acids
-
Retards oxidative stress
- Prevents wasting dis-ease
- Eases
side effects of chemotherapy and radiotherapy
3) Pulmonary
Glutathione is the most efficient free radical
(acid) scavenger in the airways, and dozens of studies have confirmed
that free radical (acid) damage is a primary player in Chronic
Obstructive Pulmonary Disease. Rahman I, MacNee W. Oxidative Stress
and Regulation of Glutathione in Lung Inflammation. Eur Respir J. 2000
Sep; 16(3):534-54.
- Breaks up mucus - Rahman
I, MacNee W. Oxidative Stress and Regulation of Glutathione in Lung
Inflammation. Eur Respir J. 2000 Sep; 16(3):534-54
-
Cystic fibrosis - Glutathione neutralized harmful
oxidants introduced into the lungs or those released by cells. Exotoxins
from bacteria can overload the endobronchial terrain and feed the fires
of acidic inflammation. This staggering burden increases the oxidative
sensitivity of the CF lung, resulting in further injury of lung
parenchyma. Data supports evidence of a decrease in the antioxidant
tri-peptide glutathione (Roum JH, Buhl R, McElvaney NG, et al.
Systemic Deficiency of Glutathione in Systic Fibrosis. J Appl
Physiol 1993; 75:19-24).
- Asthma
- Chronic bronchitis
- Emphysema -
Lamson, David, MD, Grignall, Matthew, ND. The use of Nebulized
Glutathione in the Treatment of Emphysema: A Case Report. Altern Med
Review. 5(5);429-431, 2000 Oct.
- Pulmonary fibrosis
- Ishii T, Fujishiro M, Nakajima J, Teramoto S, Ouchi Y,
Matsuse T. Depletion of Glutathione S-Transferase P1 Induces Apoptosis
in Huamn Lung Fibroblasts. Exp Lung Res. 29(7);523-36, 2003 Oct-Nov.
4) Aging
Glutathione is
critically important to our brain as it is one of the most important
brain antioxidants. Glutathione helps preserve brain tissue by
preventing damage from free radicals (acids).
In addition to
quenching dangerous acids, glutathione also acts to recycle vitamin E
which also has the ability to reduce acidity in the brain. (Perlmutter
D., BrainRecovery.com July 2004, 5th ed:13)
-
Autism - Medical literature documents that an
out-fection can lead to a lowering of glutathione which participates in
detoxification, interacts with metallothioneins, and supports many
crucial aspects of immunity. A link between glutathione and autism
regression may derive from the fact that transient or chronic intestinal
problems can impair an infant's or toddler's nutritional status, thereby
minimizing the levels of amino-acids required for the production of
glutathione (McCandless, J. Children With Starving Brains. 2003, 2nd
ed; 252)
- Parkinson's Disease - Glutathione
helps to preserve brain tissue by preventing damage from free
radicals (acids) and destructive chemicals formed by the normal
processes of metabolism, toxic elements in the environment, and as a
normal response of the body to challenges by acidic agents or other
stresses. With the understanding that glutathione is important for
brain protection and that this protection many be lacking in the brains
of Parkinson's clients due to glutathione deficiency, it can be seen as
very beneficial. (Di Monte DA, Cahn P, Sandy MS. Glutathione in
Parkinson's Disease: A Link Between Oxidative Stress and Mitochondrial
Damage? An Neurol. 32 Suppl; S111-115, 1992.)
-
Alzheimer's Dis-ease - Woltjer, R.L., Hgheim W.,
Maezawa I., Vaisar T, Montine K.S., Montine T.J., Role of Glutathione in
Intracellular Amyloid-Alpha Recursor Protein/Carboxy- Terminal Fragment
Aggregation and Associated Cytotoxicity. J Neurochem. 2005 May; 93 (4):
1047-56.
- Huntington's Dis-Ease - Choo Y.S.,
Mao Z, Johnson GV, Lesort M. Increased Glutathione Levels In Cortical
Striatal Mitochondria of the R6/2 Huntington's Disease Mouse Model.
Neuroscience Letter. 2005 Sep 23; 386(1): 63-8.
-
Multiple Sclerosis - Calabrese V, Scapaginini G,
Ravagna A, Bella R, Butterfield DA, Calvani M, Pennisi G, Giuffrida
Stella AM. Disruption of Thiol Homeostasis and Nitrostative Stress in
the Cerebrospinal Fluid of Patients with Active Multiple Sclerosis:
Evidence for a Protective Role of Acetylcarnitine. 2003 Sep; 28(9):
1321-8. Mann CL, Davies MB, Aldersea J, Fryer AA, Jones PK, Ko Ko C,
Young C, Strange RC, Hawkins CP. Glutathione S-Transferase Polymorphisms
in MS: Their Relationship to Disability. Neurology. 2000 Feb
8;54(3):542-7.
- ALS - Tohgi H, Abe T, Yamazaki
K, Murata T, Ishizake E, Isobe C. Increase in Oxidized Products and
Reduction in Oxidized Glutathione in Cerborospinal Fluid From Patients
with Sporadic Form of Amyotrophic Lateral Sclerosis. Neurosci Lett. 1999
Feb 5; 260(3):204-6.
- Cataract
formation
- Macular degeneration
- Cancers of aging
-
Prostate problems
- Osteoarthritis -
Hammarqvist F, Luo JL, cotgreave IA, Andersson K, Wernerman J.
Skeletal Muscle Glutathione is Depleted In Critically Ill
Patients. Crit Care Med. 25(1):78-84 1997 Jan.
5)
Digestive
- Inflammatory bowel
dis-ease
- Hepatitis
- Malnutrition
- Pancreatitis
-
Peptic ulcer
6) Toxicology
-
Detoxifies certain drug overdoses - Acetaminophen has been
shown to reduce glutathione production, thus paving the way for
enhanced brain destruction by metabolic acids. (Perlmutter D. July 2004,
5th ed:108)
- Detoxifies substances in cigarette smoke and
auto exhaust - Rahman I, MacNee W. Lung Glutathione and Oxidative
Stress: Implications In Cigarette Smoke-Induced Airway Disease. Am J
Physiol. 277(6 Pt 1);1067-88, 1999 Dec.
- Detoxifies
pollutants including heavy metals and pesticides - Elevated
glutathione levels have been shown to protect tissue form lipid
peroxidation created by exposure to certain metals. Consider
infusions of glutathione to relieve the body burden of both neurotoxins
and metal toxicity, including mercury. (Foster, JS. Kane PC, Speight N.
The Detoxx Book. 2002;90)
- Prevents hearing loss from noise
pollution
- Detoxifies many well-known carcinogens
7)
Immunology
- Anti-viral for AIDS, hepatitis,
herpes, etc. - Low glutathione levels
in HIV clients may contribute to their immune deficiency since
glutathione plays an important role in the function of lymphocytes.
Some lymphocytes require adequate levels of glutathione in order to
function normally, and HIV induces oxidative stress that depletes the
cells of glutathione. Townsend DM, Tew KD, Tapero H. The Importance of
Glutathione in Human Disease. Biomed Pharmacother. 2003
May-June;57(3-4):145-55. Droge W, Holm E. Role of Cysteine and
Glutathione in HIV Infection and other Diseases Associated with Muscle
Wasting and Immunological Dysfunction. FASEB J, 11(13):1077-89 1997 Nov.
- Lyme Dis-Ease - Lyme dis-ease is a seriously
complex multi-system acidic inflammatory condition that is triggered
by bacterial exotoxins. Glutathione helps to remove exotoxic
and/or mycotoxic acids by forming a soluble compound with them,
which can then be excreted through the urine or gut. (Can
Glutathione Help Lyme Disease Sufferers? Excerpt from: The Glutathione
Report: Optimal Health with the Master Antioxidant, Issue 4, Volume 1,
May 2004).
- Natural antibiotic
- Chronic
fatigue syndrome - An article in the journal of Medical
Hypothesis proposed that glutathione, an antioxidant essential
for lymphocyte function, may be depleted in Chronic Fatigue
Syndrome patients. Glutathione is needed for both the immune
system and for aerobic muscular contraction. The authors proposed
that glutathione depletion by an activated immune system also causes the
muscular fatigue and myalgia associated with Chronic Fatigue Syndrome
(Bounous et al. 1999).
8) Metabolic
- Athletic
enhancement
- Decreases recovery time from physical stress
-
Supports hemoglobin in kidney failure -
Diabetes
- The blood and tissues of diabetics are marked by critically low
glutathione levels. Glutathione depletion may have adverse consequences
in diabetic clients independent of glycemic control, and it may weaken
the defense against oxidative stress. De Mattia G, Bravi MC,
Laurenti O, Cassone-Faldetta M, Armiento A, Ferri C, Falsano F.
Influence of Reduced Glutathione Infusion on Glucose Metabolism in
Patients with Non-insulin Dependent Diabetes Mellitus. Metabolism. 1998
Aug;47(8):433-8.
Glutathione provides the body with tools to
fight off these threats naturally. Healthy people also benefit from
elevated glutathione levels through an enhanced ability to fight off
acidic toxins, dis-ease, pre-cancerous cells and
the aging process itself. Diminished glutathione
levels are a symptom of aging and are particularly evident in such
aliments as Parkinson's dis-ease and Alzheimer's dis-ease.
Glutathione is also important to physically active
people. Many world-class athletes are discovering that
well-maintained glutathione levels gives them the edge over their
competitors, bringing greater strength and endurance, decreased recovery
time from injury, less muscle pain and fatigue, and muscle-promoting
activity.
Putting It All Together
1) Medical
science is still ascertaining all the critical roles played by
glutathione in dis-ease resistance and general good health. Clinical
evidence links low glutathione levels to the most common illnesses of
our time as well as newly emerging dis-eases.
2) As an essential
aid to health, glutathione works as the master
antioxidant in our body, optimizes the white blood cells
and detoxifies a long list of pollutants and carcinogens or acids.
The best way to raise glutathione levels is by eating foods that are
high in glutathione or concentrate precursor.
--------------------------------------------------
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